CCAN complex forms the Inner Kinetochore

 

The kinetochore is composed of two regions:

     (1) Inner region = CCAN complex;

     (2) Outer region = KMN (KNL-1 complex, Mis12 complex, and Ndc80 complex) network.

The CCAN is attached to the chromatids whilst the KMN network is linked to the microtubules.

➜ The CCAN Complex

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