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                                                                                                        I want to know the: 📕Function    📕Interfaces    📕Interactions    📕Conservation of CHL4 N-terminal.

CCAN complex

CCAN complex (Adopted from PDB 6QLD)

 

 

Kinetochore is an important protein in cell cycle. Here we will present the inner part of kinetochore called Constitutive Centromere-Associated Network (CCAN), and focus on the protein-protein interactions of the N-terminal of its CHL4 chain and other subunits.

 

As a part of kinetochore, CCAN presents during the whole cell cycle. One of its biological roles is managing chromosomes segregation during mitoses, which is vital for cell proliferation.

 

🔔Click here to know more about CCAN in chromosomes segregation.

 

 

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