Introduction

Accurate and systematic segregation of chromosomes during mitosis and meiosis maintains genome stability and is hence vital for the propagation of all life. Kinetochores initiate, control and monitor chromosomal movement by serving as attachment points for the microtubules of mitotic spindle.¹ 

This exhibit focuses on the CTF3 subunit of the inner kinetochore CCAN (Constitutive Centromere-Associated Network) complex of Saccharomyces cerevisiae and further explains the nature of the interface formed by its interaction with other subunits of the complex.

References

1.        Maiato, H., DeLuca, J., Salmon, E. D. & Earnshaw, W. C. The dynamic kinetochore-microtubule interface. Journal of Cell Science 117, 5461–5477 (2004).