Exploring Affinity through Non-Covalent Bonding
To recap how CHL4 (Cenp-N) and IML3 (Cenp-L) (i.e. Cenp-LN complex) interact within the complex and with each other, browse the following exhibits:
- Exploring the kinetochore protein Iml3 (Cenp-L)
- The Inner Kinetochore Cenp-N N-terminal
- A Closer Look into the Inner Kinetochore – CCAN Cenp-N C-terminal
Non-covalent bonding contributes to how strong the protein-protein interactions are between interfaces. Indeed, the different types of bonding contribute varying energies to stabilise these interactions:
- Salt bridges : 2 - 4 kcal/mol
- Hydrogen bonds : 0.4 - 2 kcal/mol
- Van der Waals forces : 0.05 - 0.1 kcal/mol
To know more, why not continue exploring this exhibit ...