Hydrophobicity of atoms and residues
The figures below show that the H-bonds in the interfaces are composed mostly of hydrophilic residues and atoms, while Van der Waals' interactions are formed by hydrophobic residues and atoms. The hydrophobic effect may also participate in the formation of both IML3 complexes at their interfaces.
Fig.1 Frequency of bonds and amino acids at the interfaces distributed by hydrophobicity and bond type.
Fig.2 Frequency of atoms at the interfaces based on hydrophobicity and bond type.